Reported Resistance Case(s)

Species: spodoptera litura

Order	Family	Common Name(s)	Group	Host
lepidoptera	noctuidae	mediterranean climbing cutworm	AG	Tobacco

Active Ingredient: cyantraniliprole

MOA: Ryanodine receptor modulators, Diamides
Group: DIA	CAS #: 736994-63-1	Shaugnessy Code: 0

Resistance Case(s)

Case Id	Year of Report	Type of Resistance	Location	Reference
G23471	2025	Field Evolved Resistance	China-- Guangdong-- Huizhou	Mei W, Yang G, Ye G, Yang Y, Wu Y. (2025). Differential contributions of the ryanodine receptor I4723M and I4723K mutations to diamide resistance in Spodoptera litura. Pestic Biochem Physiol, 208.
G23472	2025	Field Evolved Resistance	China-- Guangdong-- Huizhou	Mei W, Yang G, Ye G, Yang Y, Wu Y. (2025). Differential contributions of the ryanodine receptor I4723M and I4723K mutations to diamide resistance in Spodoptera litura. Pestic Biochem Physiol, 208.
G22543	2023	Field Evolved Resistance	China-- Fujian-- Ningde	Mei, W., Zuo, Y., Su, T., Yuan, J., Wu, Y., & Yang, Y. (2023). The ryanodine receptor mutation I4728M confers moderate-level resistance to diamide insecticides in Spodoptera litura. Pest management science, 79.
G22676	2022	Field Evolved Resistance	China-- Guangdong-- Guangzhou	Zhang, Ziyi, Bingli Gao, Cheng Qu, Jingyu Gong, Wenxiang Li, Chen Luo, and Ran Wang. (2022). Resistance Monitoring for Six Insecticides in Vegetable Field-Collected Populations of Spodoptera litura from China. Horticulturae, 8.
G22680	2022	Field Evolved Resistance	China-- Hainan-- Sanya	Zhang, Ziyi, Bingli Gao, Cheng Qu, Jingyu Gong, Wenxiang Li, Chen Luo, and Ran Wang. (2022). Resistance Monitoring for Six Insecticides in Vegetable Field-Collected Populations of Spodoptera litura from China. Horticulturae, 8.
G22684	2022	Field Evolved Resistance	China-- Yunnan-- Yuxi	Zhang, Ziyi, Bingli Gao, Cheng Qu, Jingyu Gong, Wenxiang Li, Chen Luo, and Ran Wang. (2022). Resistance Monitoring for Six Insecticides in Vegetable Field-Collected Populations of Spodoptera litura from China. Horticulturae, 8.

*The population was created solely by selection and/or genetic manipulation.
**The population was selected further in the laboratory after collection.