Reported Resistance Case(s)

Species: spodoptera frugiperda

Order	Family	Common Name(s)	Group	Host
lepidoptera	noctuidae	fall armyworm	AG	cotton, grains, grasses, sugarcane

Active Ingredient: flubendiamide

MOA: Ryanodine receptor modulators, Diamides
Group: DIA	CAS #: 272451	Shaugnessy Code: 0

Resistance Case(s)

Case Id	Year of Report	Type of Resistance	Location	Reference
G23489	2025	Lab selected after field-evolved resistance**	Brazil-- Bahía-- Luis Eduardo Magalhães	Thiesen LV, Gonçalves GC, Guidolin AS, Nascimento AR, Coutinho EF, Borba JP, Picelli EC, Omoto C. (2025). Characterization of cyantraniliprole resistance in Spodoptera frugiperda: Selection, inheritance pattern, and cross-resistance to other diamide insecticides.. Pest Manag Sci, 81.
G22635	2024	Field Evolved Resistance	Puerto Rico-- Ponce	Posos-Parra, O., Mota-Sanchez, D., Pittendrigh, B. R., Wise, J. C., DiFonzo, C. D., & Patterson, E. (2024). Characterization of the inheritance of field-evolved resistance to diamides in the fall armyworm (Spodoptera frugiperda) (Lepidoptera: Noctuidae) population from Puerto Rico. PloS one, 19.
G22318	2022	Lab selected after field-evolved resistance**	Brazil	Okuma, D. M., Cuenca, A., Nauen, R., & Omoto, C. (2022). Large-Scale Monitoring of the Frequency of Ryanodine Receptor Target-Site Mutations Conferring Diamide Resistance in Brazilian Field Populations of Fall Armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae).. Insects, 13.
G22316	2022	Lab selected after field-evolved resistance**	Brazil	Okuma, D. M., Cuenca, A., Nauen, R., & Omoto, C. (2022). Large-Scale Monitoring of the Frequency of Ryanodine Receptor Target-Site Mutations Conferring Diamide Resistance in Brazilian Field Populations of Fall Armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae).. Insects, 13.
G21984	2022	Lab selected after field-evolved resistance**	Brazil	Okuma, D.M.; Cuenca, A.; Nauen, R.; Omoto, C. (2022). Large-Scale Monitoring of the Frequency of Ryanodine Receptor Target-Site Mutations Conferring Diamide Resistance in Brazilian Field Populations of Fall Armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae).. Insects, 13.
G21983	2022	Lab selected after field-evolved resistance**	Brazil	Okuma, D.M.; Cuenca, A.; Nauen, R.; Omoto, C. (2022). Large-Scale Monitoring of the Frequency of Ryanodine Receptor Target-Site Mutations Conferring Diamide Resistance in Brazilian Field Populations of Fall Armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae).. Insects, 13.
G21586	2022	Field Evolved Resistance	Brazil-- São Desidério	Okuma, D. M., Cuenca, A., Nauen, R., and Omoto, C. (2022). Large-Scale Monitoring of the Frequency of Ryanodine Receptor Target-Site Mutations Conferring Diamide Resistance in Brazilian Field Populations of Fall Armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae). 13 626.
G21585	2022	Field Evolved Resistance	Brazil-- São Desidério	Okuma, D. M., Cuenca, A., Nauen, R., and Omoto, C. (2022). Large-Scale Monitoring of the Frequency of Ryanodine Receptor Target-Site Mutations Conferring Diamide Resistance in Brazilian Field Populations of Fall Armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae). 13 626.
G20036	2018	Field Evolved Resistance	Puerto Rico-- Ponce	Gutiérrez-Moreno, R., Mota-Sanchez, D., Blanco, C. A., Whalon, M. E., Terán-Santofimio, H., Rodriguez-Maciel, J. C., and DiFonzo, C. (2018). Field-evolved resistance of the fall armyworm (Lepidoptera: Noctuidae) to synthetic insecticides in Puerto Rico and Mexico. Journal of Economic Entomology.
G20037	2018	Field Evolved Resistance	Mexico-- Sinaloa-- Los Mochis	Gutiérrez-Moreno, R., Mota-Sanchez, D., Blanco, C. A., Whalon, M. E., Terán-Santofimio, H., Rodriguez-Maciel, J. C., and DiFonzo, C. (2018). Field-evolved resistance of the fall armyworm (Lepidoptera: Noctuidae) to synthetic insecticides in Puerto Rico and Mexico. Journal of Economic Entomology.

*The population was created solely by selection and/or genetic manipulation.
**The population was selected further in the laboratory after collection.