Reported Resistance Case(s)

Species: spodoptera litura

Order	Family	Common Name(s)	Group	Host
lepidoptera	noctuidae	mediterranean climbing cutworm	AG	Tobacco

Active Ingredient: chlorantraniliprole

MOA: Ryanodine receptor modulators, Diamides
Group: DIA	CAS #: 500008-45-7	Shaugnessy Code: 0

Resistance Case(s)

Case Id	Year of Report	Type of Resistance	Location	Reference
G23491	2025	Lab selected after field-evolved resistance**	Australia-- Broome-- Northwestern	Bird LJ, Dunn NM. (2025). Quantitative genetic analysis of diamide resistance in Australian Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae). Sci Rep, 15.
G23470	2025	Field Evolved Resistance	China-- Guangdong-- Huizhou	Mei W, Yang G, Ye G, Yang Y, Wu Y. (2025). Differential contributions of the ryanodine receptor I4723M and I4723K mutations to diamide resistance in Spodoptera litura. Pestic Biochem Physiol, 208.
G23469	2025	Field Evolved Resistance	China-- Guangdong-- Huizhou	Mei W, Yang G, Ye G, Yang Y, Wu Y. (2025). Differential contributions of the ryanodine receptor I4723M and I4723K mutations to diamide resistance in Spodoptera litura. Pestic Biochem Physiol, 208.
G22861	2024	Field Evolved Resistance	China-- Jiangxi-- Nanchang	Qu, C., Li, Y., Zhan, Q., Wang, J., Luo, C., Guedes, R. N. C., & Wang, R. (2024). Tetraniliprole risk assessment: Unveiling a hidden threat for managing a generalist herbivore. Environmental research, 256.
G22542	2023	Unspecified	China-- Fujian-- Ningde	Mei, W., Zuo, Y., Su, T., Yuan, J., Wu, Y., & Yang, Y. (2023). The ryanodine receptor mutation I4728M confers moderate-level resistance to diamide insecticides in Spodoptera litura. Pest management science, 79.
G22683	2022	Field Evolved Resistance	China-- Yunnan-- Yuxi	Zhang, Ziyi, Bingli Gao, Cheng Qu, Jingyu Gong, Wenxiang Li, Chen Luo, and Ran Wang. (2022). Resistance Monitoring for Six Insecticides in Vegetable Field-Collected Populations of Spodoptera litura from China. Horticulturae, 8.
G22679	2022	Field Evolved Resistance	China-- Hainan-- Sanya	Zhang, Ziyi, Bingli Gao, Cheng Qu, Jingyu Gong, Wenxiang Li, Chen Luo, and Ran Wang. (2022). Resistance Monitoring for Six Insecticides in Vegetable Field-Collected Populations of Spodoptera litura from China. Horticulturae, 8.
G22675	2022	Field Evolved Resistance	China-- Guangdong-- Guangzhou	Zhang, Ziyi, Bingli Gao, Cheng Qu, Jingyu Gong, Wenxiang Li, Chen Luo, and Ran Wang. (2022). Resistance Monitoring for Six Insecticides in Vegetable Field-Collected Populations of Spodoptera litura from China. Horticulturae, 8.
G22673	2022	Field Evolved Resistance	China-- Fujian-- Ningde	Zhang, Ziyi, Bingli Gao, Cheng Qu, Jingyu Gong, Wenxiang Li, Chen Luo, and Ran Wang. (2022). Resistance Monitoring for Six Insecticides in Vegetable Field-Collected Populations of Spodoptera litura from China. Horticulturae, 8.
G21529	2022	Field Evolved Resistance	China-- Yunnan-- Yuxi	Zhang, Z., Gao, B., Qu, C., Gong, J., Li, W., Luo, C., and Wang, R. (2022). Resistance Monitoring for Six Insecticides in Vegetable Field-Collected Populations of Spodoptera litura from China. Horticulturae, 8 255.
G20260	2019	Field Evolved Resistance	China-- Guangdong Province-- Huizhou	Wang X., Lou, L., and Su J. (2019). Prevalence and stability of insecticide resistances in field population of T Spodoptera litura (Lepidoptera: Noctuidae) from Huizhou, Guangdong Province, China. Journal of Asia-Pacific Entomology, 22 728-732.
G16649	2014	Lab selected after field-evolved resistance**	India-- Tamilnadu-- Salem	Muthusamy, R., Vishnupriya, M., and Shivakumar, M. S. (2014). Biochemical mechanism of chlorantraniliprole resistance in Spodoptera litura (Fab) (Lepidoptera: Noctuidae). Journal of Asia-Pacific Entomology, 17 865-869.
G16648	2014	Field Evolved Resistance	India-- Tamilnadu-- Salem	Muthusamy, R., Vishnupriya, M., and Shivakumar, M. S. (2014). Biochemical mechanism of chlorantraniliprole resistance in Spodoptera litura (Fab) (Lepidoptera: Noctuidae). Journal of Asia-Pacific Entomology, 17 865-869.
G14946	2012	Field Evolved Resistance	China-- Guangdong-- Huizhou	Su, J., Lai, T., and Li, J. (2012). Susceptibility of field populations of Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae) in China to chlorantraniliprole and the activities of detoxification enzymes. Crop Protection, 42 217-222.
G14947	2012	Field Evolved Resistance	China-- Guangdong-- Dongguang	Su, J., Lai, T., and Li, J. (2012). Susceptibility of field populations of Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae) in China to chlorantraniliprole and the activities of detoxification enzymes. Crop Protection, 42 217-222.
G14948	2012	Field Evolved Resistance	China-- Shanghai-- Minhang	Su, J., Lai, T., and Li, J. (2012). Susceptibility of field populations of Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae) in China to chlorantraniliprole and the activities of detoxification enzymes. Crop Protection, 42 217-222.
G14950	2012	Field Evolved Resistance	China-- Anhui-- Hefei	Su, J., Lai, T., and Li, J. (2012). Susceptibility of field populations of Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae) in China to chlorantraniliprole and the activities of detoxification enzymes. Crop Protection, 42 217-222.
G14956	2012	Field Evolved Resistance	China-- Fujian-- Zhangzhou	Su, J., Lai, T., and Li, J. (2012). Susceptibility of field populations of Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae) in China to chlorantraniliprole and the activities of detoxification enzymes. Crop Protection, 42 217-222.
G14944	2012	Field Evolved Resistance	China-- Guangdong-- Shenzheng	Su, J., Lai, T., and Li, J. (2012). Susceptibility of field populations of Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae) in China to chlorantraniliprole and the activities of detoxification enzymes. Crop Protection, 42 217-222.
G14954	2012	Field Evolved Resistance	China-- Anhui-- Hexian	Su, J., Lai, T., and Li, J. (2012). Susceptibility of field populations of Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae) in China to chlorantraniliprole and the activities of detoxification enzymes. Crop Protection, 42 217-222.
G14949	2012	Field Evolved Resistance	China-- Anhui-- Hefei	Su, J., Lai, T., and Li, J. (2012). Susceptibility of field populations of Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae) in China to chlorantraniliprole and the activities of detoxification enzymes. Crop Protection, 42 217-222.

*The population was created solely by selection and/or genetic manipulation.
**The population was selected further in the laboratory after collection.